Claudio Lattanzi is known for Zombie 5: Killing Birds (1988), Crucified (2019) and La vita è già finita? (2007). After working as Michele Soavi's assistant on a couple of occasions, he directed his own horror films, Zombie 5: Killing Birds (1987) and Crucified (2019).Claudio Lattanzi began his film career in the 1980s as an assistant director in Deliria, House 3 - Ghosthouse, Interzone and The church

Under the pseudonym Claude Milliken, in 1988 he directed. Killing Birds (also known by the title Zombi 5), a horror film produced by Joe D'Amato's Filmirage (Buio Omega, Rosso sangue), who also collaborated on the direction by directing some scenes.

In 1989, on the other hand, Claudio Lattanzi is involved in the distribution of the The House 4 - Witchcraft (directed by Fabrizio Laurenti), the second apocryphal sequel in the series Evil Dead by Sam Raimi

After a long hiatus away from filmmaking, Claudio Lattanzi returned to the director's booth in 2018 to direct Aquarius Visionarius - The Cinema of Michele Soavi, a documentary that recounts, through interviews with Dario Argento, Pietro Valsecchi, Michele Placido and Sergio Stivaletti, the career of Michele Soavi (The Church).

The film was presented at the Sitges Film Festival along with the horror film Everybloody's End which he is directing in 2019.

Finally in 2023 he signs the direction of Dream time, a docufilm on Italian horror films of the 1980s-1990s, shedding light on the characters who left an indelible mark on that period (Lamberto Bava, Michele Soavi, Claudio Simonetti, Fabio Frizzi, Sergio Stivaletti, Antonio Tentori).